A history of leadership in institutions:

• Director, National Institute of Neurological Disorders and Stroke, NIH.  (2003-2014)
  • Co-Chair, New Investigators Committee; NIH Stem Cell Task Force:  Co-Chair Neuroscience Blueprint;
• Scientific Director, National Institute of Neurological Disorders and Stroke, NIH. (1995-2003)
• Professor and Chair, Department of Neuroscience, Case Western Reserve Medical School (1990-1995)

Leadership in national forums:

• Member, Institute of Medicine Forum on Neuroscience and Nervous System Disorders (2006–)
  • Vice Chair, Forum on Neuroscience and Nervous System Disorders (2015–)
• Council, National Academy of Medicine (2017–)
• President-elect, Society for Neuroscience (2002; resigned because of appointment to the NIH)