Clinical research is vital, but is also expensive and often slow.  It is essential that its basic science underpinning be accurate and reliable.  Dr. Landis organized and introduced a symposium at the annual meeting of the Society for Neuroscience November 16, 2014, that addressed the importance of reproducibility, and explored the tools and techniques that can support that goal.  A panel of gifted investigators explored a range of topics, ranging from training to scientific review and publication.